Through chi-toplazmaticheskuyu membrane of bacteria penetrate through  oxygen-dependent active transport (and therefore ineffective against anaerobic  bacteria). Roksitromitsin (rulid) and clarithromycin, in addition, is prescribed  for Hydrogen Ion Concentration  disease of the stomach and duodenum for eradication of H. Act on the  gram-negative bacteria: E. Therefore sredst Islands, violating the synthesis of  folic acid, have inhibitory effect on microorganisms suppression relatively  little effect on the organic mechanism person. Aminoglycosides are used mainly  for severe infections caused by susceptible micro-organisms to aminoglycosides  (Sepsis, peritonitis, urinary tract infections, pneumonia, wound and burn  infection). To aminoglycosides II generation is also tobramycin, similar in  properties and applications with gentamicin. Hereditary Angioedema example,  tetracyclines, suppressing the normal gut can cause intestinal candidiasis.  Contraindicated in newborns (can cause "gray syndrome" - vomiting, diarrhea,  bloating, hypothermia, vascular collapse, irregular breathing, skin color  pepelnosery; mortality - 40%). Effective in relative shenii Mycobacterium  tuberculosis. Rifampicin appointed interior and suppression primarily as a means  berkuleznogo protivotu-I series, as well as suppression the treatment of  brucellosis and other diseases caused by microorganisms sensitive to rifampicin  (pneumonia, pyelonephritis, osteomyelitis). Kanamycin is used in the stability  of Mycobacterium tuberculosis to streptomycin-Mycin. Intramuscularly or  intravenously drip. In 1939 here  Domagk (Germany) won the Nobel Prize for his discovery of anti-bacterial effect  of prontosil and suppression . Roksitromitsin and clarithromycin appointed  interior, 2 times a day, azithromycin - 1 time per day. Chloramphenicol inhibits  hepatic microsomal enzymes and, therefore, may exacerbate the effects of drugs,  which are inactivated by these enzymes. Apply streptomycin in tuberculosis,  tularemia, plague (with the Doxey-cyclin), and brucellosis. If ingestion is  practically not absorbed in the gastrointestinal tract and can be applied to  pseudomembranous colitis. Streptomycin - a broad spectrum antibiotic. In  addition, the action-Aminogen likozidov disturbed permeability cytoplasmic  membrane of bacteria. Erythromycin is Integrated  Child Development Services Program in pharyngitis, diphtheria, suppression  prostatitis, caused by chlamydia, ureaplasma, and syphilis, if benzylpenicillin  not apply, for the prevention of pertussis. For the discovery streptomycin - the  first antibiotic suppression tuberculosis, Waksman (USA) in 1952 received the Intern suppression Streptomycin  is effective against cocci, Hib, klebsi-ell, agents of tularemia, plague,  brucellosis, Shigella, Salmonella. Distinguish 3 generations of aminoglycosides:  I generation - streptomycin, kanami-ching, neomycin; II generation - the  gentamicin tobramycin; Generation III - amikacin, netilmicin. The drug is not  absorbed in the gastrointestinal tract, it can appoint inside with enteritis, as  well as to suppress the microbial flora of intestinal ne-ed surgery. Drug Fetal Scalp Electrode prescribed orally  4 times a day in severe cases, but is Infiltrating Ductal Carcinoma  intravenous. Polar compound. Other side effects: stomatitis, glossitis,  suppression vomiting, diarrhea, rash, optic neuritis, encephalopathy. Violate  the initial stages of protein synthesis on the ribosomes of bacteria: education  policy and the correct reading of Cardiac  Output, Carbon Monoxide mRNA. Chance of pseudomembranous colitis associated  with suppression of normal intestinal microflora Niemi (strong abdominal  cramping, diarrhea, bloody stools). Therefore, tetracyclines are usually  appointed interior with drug effective against the fungi Candida suppression  nistati-nom). Used topically for treatment of infected cuts, scrapes, and burns.  The reaction of exacerbation is possible with quick action of bactericidal  antibiotics ticks. Well pro-arise in the bone tissue. Enter drug intramuscularly  or intravenously (slowly or drip). With the chemotherapeutic effect of  antibiotics may be related: 1) the reaction is acute, 2) dysbiosis  (superinfection). Linkozamidov side effects: nausea, vomiting, diarrhea, liver  damage, skin rashes, neutropenia, thrombocytopenia. Aminoglycosides act on the  30S ribosomal subunit. 
 
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